Levels of plasma lipid peroxide products and antioxidant status in rheumatoid arthritis.
Southeast Asian J Trop Med Public Health
;
2000 Jun; 31(2): 335-8
Artigo
em Inglês
| IMSEAR
| ID: sea-32205
ABSTRACT
Oxygen free radicals have been implicated as mediators of tissue damage in patients with rheumatoid arthritis. The aim of our study was to assess the lipid peroxide products and antioxidant status in rheumatoid arthritis patients (RA). The study involved determination of two plasma lipid peroxide products, malondialdehyde (MDA) and conjugated dienes (CD), two plasma antioxidant vitamins (C and E) in 91 RA patients and 26 healthy subjects. The results showed that rheumatoid patients had increased plasma CD but not MDA and decreased plasma vitamin E, when properly expressed per unit cholesterol and triglyceride. This finding suggested that RA patients had increased oxidant stress that might play a role in the tissue damage and inflammation process of this disease.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Artrite Reumatoide
/
Ácido Ascórbico
/
Vitamina E
/
Idoso de 80 Anos ou mais
/
Idoso
/
Feminino
/
Humanos
/
Adulto
/
Peróxidos Lipídicos
/
Malondialdeído
Limite:
Aged80
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2000
Tipo de documento:
Artigo
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