Cell-bound haemagglutinin (CHA) of V. cholerae 01 as protective antigen.
Southeast Asian J Trop Med Public Health
;
1984 Sep; 15(3): 407-13
Artigo
em Inglês
| IMSEAR
| ID: sea-32254
ABSTRACT
The study of immunogenicity of cell-bound haemagglutinin (CHA) of Vibrio cholerae E1 Tor in mice revealed that the CHA was a good antigen when it was adsorbed onto the surface of sheep red blood cells and given orally to mice. The antigen not only induced high levels of various class antibodies which sustained in the intestinal tracts for a long period of time (longer than 6 months) but also the antibodies were protective against homologous cholera challenge. The degree of protection seems to correlate with the level of IgA in the intestinal washing. The protective ability was conferred mainly by anti-CHA.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Vibrio cholerae
/
Ovinos
/
Lipopolissacarídeos
/
Cólera
/
Cromatografia em Gel
/
Imunização
/
Modelos Animais de Doenças
/
Eritrócitos
/
Hemaglutininas
/
Animais
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1984
Tipo de documento:
Artigo
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