Chronic industrial exposure to lead in 63 subjects. II. Evaluation of chelation therapy.
Southeast Asian J Trop Med Public Health
;
1976 Dec; 7(4): 569-74
Artigo
em Inglês
| IMSEAR
| ID: sea-32347
ABSTRACT
Efficacy of chelation therapy with intravenous calcium disodium edetate, oral Ca EDTA, and oral penicillamine was tested in 63 subjects with chronic minimal industrial exposure to lead. All three agents increased the urinary lead excretion. The effect was greatest with intravenous Ca EDTA, next with oral penicillamine and least with oral Ca EDTA. Symptoms, particularly colicky abdominal pain, improved during the period of chelation therapy. Anaemic subjects showed improvements in haematological parameters. It is recommended that subjects with chronic minimal industrial exposure to lead receive chelation therapy. The relative merits of the three agents are discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Penicilamina
/
Humanos
/
Masculino
/
Doença Crônica
/
Ensaios Clínicos como Assunto
/
Ácido Edético
/
Adulto
/
Exposição Ambiental
/
Chumbo
/
Intoxicação por Chumbo
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1976
Tipo de documento:
Artigo
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