Antibodies in serum of patients with clonorchiasis before and after treatment.
Southeast Asian J Trop Med Public Health
;
1995 Mar; 26(1): 114-9
Artigo
em Inglês
| IMSEAR
| ID: sea-32676
ABSTRACT
Sera of 31 patients infected with Clonorchis sinensis were examined using fraction 1 antigen by ELISA during a one-year observation. The results of ELISA with Igs, IgG and IgA demonstrated high sensitivity (100%, 100% and 90%) and specificity (100%, 100% and 87%). Sera specific Igs and IgG were significantly decreased in the 3rd month after treatment with praziquantel (25mg/kg body weight in one dose), and IgA was significantly decreased in the 1st month (paired t-test, p < 0.05). No eggs were found in the stool after treatment. Detection of sera specific Igs, IgG and IgA by ELISA was combined with stool examination to evaluate the effect of praziquantel and the completeness of the cure.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Praziquantel
/
Isotipos de Imunoglobulinas
/
Feminino
/
Humanos
/
Masculino
/
Ensaio de Imunoadsorção Enzimática
/
Anticorpos Anti-Helmínticos
/
Sensibilidade e Especificidade
/
Clonorquíase
/
Clonorchis sinensis
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo diagnóstico
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1995
Tipo de documento:
Artigo
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