Motility and drug susceptibility of Angiostrongylus cantonensis developing from gamma-irradiated first-stage larvae.
Southeast Asian J Trop Med Public Health
;
1987 Dec; 18(4): 547-51
Artigo
em Inglês
| IMSEAR
| ID: sea-32834
ABSTRACT
The effects of neuropharmacological agents on the motility of irradiated and non-irradiated Angiostrongylus cantonensis adult females were studied. GABA induced complete paralysis in non-irradiated and 5,000 R-irradiated worms, but caused only slight paralysis on 10,000 R-irradiated worms. The paralytic effect of GABA was antagonised by picrotoxin. The reason for low susceptibility of heavily irradiated worms to GABA is not known. There was no difference in susceptibility of non-irradiated and irradiated worms to other neuropharmacological agents including eserine, phenylephrine and dibenamine.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fenilefrina
/
Fisostigmina
/
Picrotoxina
/
Ratos
/
Ratos Endogâmicos
/
Fármacos do Sistema Nervoso Autônomo
/
Estricnina
/
Feminino
/
Masculino
/
Convulsivantes
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1987
Tipo de documento:
Artigo
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