Clinicopathological profile of bronchogenic carcinoma in Bangladesh.

ABSTRACT

This study reflects some of the basic facts and present status of bronchogenic carcinoma in Bangladesh. Of the total patients admitted in one surgical unit of IDCH during the period 1983 to 1986, 28.7 were clinically suspected to be suffering from bronchogenic carcinoma. Males largely dominated the females (82.4 percent as against 17.6 percent) giving a ratio of 4.61.0, and more than 90 percent of the victims were heavy smokers. All the suspected patients were then subjected to radiological examination of chest, bronchoscopic examination (73.0 percent), histopathological examination of the bronchial biopsy specimen and sputum cytological examination (63.2 percent) cases. Bronchoscopic examination revealed endobronchial tumor or suspicious lesion in 63.2 percent cases. The sputum cytological examination were positive for malignant cells in 35.6 percent cases. Histopathological gradation of the carcinoma in order of frequencies were squamous cell carcinoma (13.3 percent), large cell carcinoma (9.7 percent) and adenocarcinoma (4.2 percent) respectively. About one fourth of the cases (27.6 percent) were found to be clinically suitable for operation but on thoracotomy resectability was possible only in 20.6 percent cases. Inoperable cases were subsequently referred for radio or chemotherapy. Follow-up of the cases were rather difficult.