Studies on human filariasis in Malaysia: immunodiagnosis using indirect immunofluorescence.
Southeast Asian J Trop Med Public Health
;
1979 Dec; 10(4): 486-97
Artigo
em Inglês
| IMSEAR
| ID: sea-33623
ABSTRACT
The indirect immunofluorescence test using sonicated microfilariae of Brugia malayi has been evaluated on 173 sera from patients and persons exposed to Wuchereria bancrofti and B. malayi in endemic areas of Peninsular Malaysia. In the microfilaria-negative group, without signs and symptoms of filariasis 55/62 sera (89%) had titers of 116 and less. In the microfilaremic groups and in the amicrofilaremic cases with clinical filariasis, all the sera tested were positive, with the antibody titers ranging generally from 116 - 1256. Cross-reaction tests were done on 16 samples of onchocerciasis sera from West Africa using sonicated antigen as well as antigen-coated CNB1-activated sepharose. Antibody titers were detected in all the sera. The usefulness of the sonicated microfilarial antigen in serodiagnosis of filariasis is discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Wuchereria bancrofti
/
Brugia
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Pré-Escolar
/
Imunofluorescência
/
Adolescente
/
Adulto
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1979
Tipo de documento:
Artigo
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