Clostridium difficile infections in HIV-positive patients.
Southeast Asian J Trop Med Public Health
;
2000 Sep; 31(3): 537-9
Artigo
em Inglês
| IMSEAR
| ID: sea-33635
ABSTRACT
The prevalence of Clostridium difficile infections in HIV-positive patients with regard to the presence of its enterotoxin was investigated. Enzyme immunoassay (EIA, Meridian Diagnostic Inc) was used for the detection of C. difficile enterotoxin in stool specimens collected from 201 HIV-positive and 271 HIV-negative diarrheal patients. Culture was performed on cycloserine cefoxitin fructose agar. Chromosomal DNA types of C. difficile isolates were determined by pulsed-field gel electrophoresis (PFGE). In the HIV-positive group, C. difficile enterotoxin was found in 58.8% and 12.6% of diarrheal and non-diarrheal patients, repectively, whereas this toxin was found in 36.5% of HIV-negative-diarrheal patients. However, 13.6% of stool samples were negative by toxin assay, but were positive for C. difficile by culture and latex agglutination test. Among 11 isolates from both HIV-positive and HIV-negative patients, 6 patterns of PFGE type were observed A, B, C, D, E and F.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Toxinas Bacterianas
/
Humanos
/
DNA Bacteriano
/
Enterocolite Pseudomembranosa
/
Clostridioides difficile
/
Técnicas Imunoenzimáticas
/
Eletroforese em Gel de Campo Pulsado
/
Infecções Oportunistas Relacionadas com a AIDS
/
Enterotoxinas
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2000
Tipo de documento:
Artigo
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