Studies on the chemotherapy of human opisthorchiasis in Thailand: I. Clinical trial of praziquantel.
Southeast Asian J Trop Med Public Health
;
1980 Dec; 11(4): 528-31
Artigo
em Inglês
| IMSEAR
| ID: sea-33707
ABSTRACT
Praziquantel (Embay 8440) was found to be effective in eliminating egg of Opishtorchis viverrini. from the stools of 49 patients. Two regimens were used Group I patients received 25 mg/kg body weight three times daily after meals for two consecutive days and Group II patients received 25 mg/kg body weight three times daily after meals for one day. In both groups eggs were not detected in the faeces by day 60 and up to 4-8 months post treatment. Mild transient side effects were present in approximately 80% of patients of Group I, with milder side effects reported in Group II. Severe diarrhoea was present on day 0 in one patient from each group. Side reactions included headache, dizziness, myalgia and lassitude, however, no laboratory evidence of toxicity was detected.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Opistorquíase
/
Praziquantel
/
Tailândia
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Ensaios Clínicos como Assunto
/
Adolescente
/
Adulto
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1980
Tipo de documento:
Artigo
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