Antimutagenic activity of Sesbania javanica Miq. flower DMSO extract and its major flavonoid glycoside.
Southeast Asian J Trop Med Public Health
;
2005 Nov; 36(6): 1543-51
Artigo
em Inglês
| IMSEAR
| ID: sea-33929
ABSTRACT
The antimutagenic activity of Sesbania javanica Miq. or Sano, an edible vegetable flower DMSO extract against aflatoxin B1 (AFB1) benzo (a) pyrene [B(a)P], was evaluated by means of the Ames' test. The Sesbania javanica Miq. flower DMSO extract showed a strong inhibitory effect against AFB1 and B(a)P mutagens. A search to isolate the major flavonoid in Sesbania javanica Miq. flower extract found the flavonol glycoside, Quercetin 3-2(G)-rhamnosylrutinoside, which was confirmed by its physicochemical properties as a major constituent of the flower. Quercetin 3-2(G)-rhamnosylrutinoside (207 microg/plate) also showeda strong inhibitory effect against AFB1 and B(a)P with a more than 70% inhibition rate.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Flavonoides
/
Humanos
/
Extratos Vegetais
/
Dimetil Sulfóxido
/
Antimutagênicos
/
Aflatoxina B1
/
Flores
/
Sesbania
/
Glicosídeos
/
Testes de Mutagenicidade
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2005
Tipo de documento:
Artigo
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