Serum alpha-1 antichymotrypsin is a possible growth inhibitor of Plasmodium falciparum.
Southeast Asian J Trop Med Public Health
;
1983 Sep; 14(3): 349-52
Artigo
em Inglês
| IMSEAR
| ID: sea-34255
ABSTRACT
Serum protease inhibitors were determined in paired sera from 7 patients with cerebral malaria and 2 patients with acute malaria showing high and low growth inhibition activity in the initial and follow-up sera respectively. Alpha-1 antichymotrypsin and alpha-1 antitrypsin but not alpha-2 macroglobulin showed direct correlation with the growth inhibition activity. When alpha-1 antitrypsin was deliberately added to the malarial culture no growth inhibition occurred indicating that the alpha-1 antichymotrypsin was the most likely factor responsible for inhibition of growth of malarial parasites in vitro.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plasmodium falciparum
/
Inibidores de Proteases
/
Humanos
/
Alfa-Macroglobulinas
/
Quimotripsina
/
Alfa 1-Antitripsina
/
Alfa 1-Antiquimotripsina
/
Inibidores do Crescimento
/
Malária
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1983
Tipo de documento:
Artigo
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