Complement and dengue haemorrhagic fever/shock syndrome.
Southeast Asian J Trop Med Public Health
;
1987 Sep; 18(3): 316-20
Artigo
em Inglês
| IMSEAR
| ID: sea-34582
ABSTRACT
The complement system is activated in DHF/DSS. The peak of activation and the presence of C3a and C5a anaphylatoxins coincided with the onset of shock and leakage. The levels of C3a correlated well with disease severity. This indicated an important role of the complement system in the pathogenesis of shock. Circulating immune complexes as assayed by two standard techniques were not detected in the majority of patients, and if detected were found in small amount. The role of circulating immune complexes in the activation of complement in DHF/DSS needs to be reinvestigated, and other possible mechanisms leading to complement activation should be sought.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Choque
/
Síndrome
/
Humanos
/
Complemento C3
/
Complemento C5
/
Complemento C3a
/
Complemento C5a
/
Ativação do Complemento
/
Dengue
/
Complexo Antígeno-Anticorpo
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1987
Tipo de documento:
Artigo
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