Angiotensin-1 converting enzyme I/D gene polymorphism: scenario in Malaysia.
Southeast Asian J Trop Med Public Health
;
2008 Sep; 39(5): 917-21
Artigo
em Inglês
| IMSEAR
| ID: sea-34601
ABSTRACT
Discrepancies in angiotensin-1 converting enzyme (ACE) allele genetic susceptibility with disease etiology have been attributed to ethnic differences. We investigated ACE gene polymorphism of the multiethnic Malaysian population by utilizing nested polymerase chain reaction. Allelic frequency of 0.65 and 0.35 for I and D allele, respectively in the pooled population was comparable with other Asian populations. A significant association was found between the Malaysian ethnic groups and ACE I/D genotype. The II genotype was found at higher frequency among the Malays but a greater frequency of DD genotype among Indians.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Polimorfismo Genético
/
Humanos
/
Reação em Cadeia da Polimerase
/
Peptidil Dipeptidase A
/
Grupos Raciais
/
Frequência do Gene
/
Genética Populacional
/
Genótipo
/
Malásia
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2008
Tipo de documento:
Artigo
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