Tachypleus lysate test for endotoxin in patients with Gram negative bacterial infections.
Southeast Asian J Trop Med Public Health
;
1979 Mar; 10(1): 13-7
Artigo
em Inglês
| IMSEAR
| ID: sea-34748
ABSTRACT
Amoebocyte lysate from the horseshoe crabs (Tachypleus gigas) which abounds in the Gulf of Thailand was used to detect endotoxin in patients with Gram-negative bacteremia, in patients with Gram-positive bacterial infections as well as in the control. The Tachypleus lysate test (TLT) was positive in 94.4% of 36 patients with Gram-negative bacteremia before initiation of antibiotic therapy. Only 4% of 50 healthy individuals were positive and all 7 patients with Gram-positive bacterial infections were negative. The threshold sensitivity of TLT was 0.625 micrograms endotoxin per ml of the plasma. In comparison with the commercial Limulus lysate test (LLT), the TLT was slightly more sensitive in exhibiting higher grade of reaction, eventhough the threshold sensitivity was the same.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Humanos
/
Sepse
/
Endotoxinas
/
Febre de Causa Desconhecida
/
Bactérias Aeróbias Gram-Negativas
/
Bactérias Anaeróbias Gram-Negativas
/
Caranguejos Ferradura
/
Teste do Limulus
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1979
Tipo de documento:
Artigo
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