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Mycobacterium tuberculosis infection among HIV/AIDS patients in Thailand: clinical manifestations and outcomes.
Southeast Asian J Trop Med Public Health ; 2002 Jun; 33(2): 346-51
Artigo em Inglês | IMSEAR | ID: sea-35196
ABSTRACT
A one year retrospective study, was conducted at Bamrasnaradura Hospital, Nonthaburi Province, Bangkok, Thailand, of 271 subjects with both TB and HIV/AIDS. Single males (median age group 31 to 40 years) were most likely to develop co-infection. The commonest clinical manifestations on initial presentation included a low grade fever, cough, weight loss, lymphadenopathy with pancytopenia, and lung infiltrates. Multi-drug resistant TB (MDR-TB) was found in 26.6% of the subjects which was significantly associated with a past history of anti-TB treatment (p = 0.005; OR=2.5); it was also significantly associated with disseminated TB (p = 0.022; OR=1.9) and mortality (p= 0.013; OR=2.8). Analysis of clinical outcomes showed that 46.7% were lost to follow-up and 13.3% had died by the time of follow-up. Among those who survived, only 11.4% had been successfully treated; the rest had not improved due to relapse (2.9%), therapeutic failure (8.8%), treatment in progress (5.9%), and failure to complete treatment (10.7%).
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Tailândia / Tuberculose / Feminino / Humanos / Masculino / Estudos Retrospectivos / Resultado do Tratamento / Infecções Oportunistas Relacionadas com a AIDS / Tuberculose Resistente a Múltiplos Medicamentos / Adulto Tipo de estudo: Estudo observacional País/Região como assunto: Ásia Idioma: Inglês Revista: Southeast Asian J Trop Med Public Health Ano de publicação: 2002 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Tailândia / Tuberculose / Feminino / Humanos / Masculino / Estudos Retrospectivos / Resultado do Tratamento / Infecções Oportunistas Relacionadas com a AIDS / Tuberculose Resistente a Múltiplos Medicamentos / Adulto Tipo de estudo: Estudo observacional País/Região como assunto: Ásia Idioma: Inglês Revista: Southeast Asian J Trop Med Public Health Ano de publicação: 2002 Tipo de documento: Artigo