Comparison of separated-lymphocyte and whole-blood lymphocyte proliferation assays for evaluating rabies-induced cellular immunity.
Southeast Asian J Trop Med Public Health
;
1996 Dec; 27(4): 715-8
Artigo
em Inglês
| IMSEAR
| ID: sea-35366
ABSTRACT
A whole-blood lymphocyte proliferation assay was compared to a standard method requiring the isolation of peripheral blood mononuclear cells (PBMC). Both methods were used to measure the cell-mediated immune responses to rabies in rabies-vaccine recipients. Whole-blood cells gave moderately higher lymphoproliferative responses in terms of stimulation indices than did separated-PBMC. The results obtained from these two methods can be considered equivalent for the purpose of quantitating cellular reactivity to rabies. The use of whole blood has advantages over the standard isolated-PBMC method.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Raiva
/
Ativação Linfocitária
/
Linfócitos
/
Imunidade Celular
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1996
Tipo de documento:
Artigo
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