Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis.
Southeast Asian J Trop Med Public Health
;
2005 May; 36(3): 650-2
Artigo
em Inglês
| IMSEAR
| ID: sea-35512
ABSTRACT
A comparative study was performed for the treatment of gnathostomiasis patients with ivermectin 0.2 mg/kg for 2 days in 15 patients vs albendazole 400 mg twice daily for 21 days in 14 patients. The ivermectin and albendazole gave cure rates of 100% and 78.5%, respectively, however the difference was not statistically significant between the two drugs (Fisher's exact, p=0.0996). One year after treatment, the patients who had no migratory swellings and a drop in ELISA titers or a negative immunoblot test were considered to be cured. The side effect of ivermectin for two days was dizziness. The side effects of albendazole were nausea, dizziness, and an increased alkaline phosphatase.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Ivermectina
/
Humanos
/
Ensaio de Imunoadsorção Enzimática
/
Albendazol
/
Resultado do Tratamento
/
Infecções por Spirurida
/
Eosinófilos
/
Gnathostoma
/
Animais
Tipo de estudo:
Ensaio Clínico Controlado
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2005
Tipo de documento:
Artigo
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