Hemoglobinopathies among five major ethnic groups in Karachi, Pakistan.
Southeast Asian J Trop Med Public Health
;
2002 Dec; 33(4): 855-61
Artigo
em Inglês
| IMSEAR
| ID: sea-35537
ABSTRACT
A brief survey of abnormal hemoglobin variants among the major ethnic groups of Karachi was conducted; 202,600 subjects were studied. Patients with low hemoglobin (Hb), low mean cell volume (MCV) and mean cell hemoglobin (MCH) including anemia, microcytosis, hypochromic hemolysis and target cells, were refered for the identification of hemoglobinopathy by molecular methods. Population screening showed that 60% had iron-deficiency anemia and 40% had hemolytic anemia, of which 20.6% was due to beta-thalassemia major, 13% beta-thalassemia trait, 5.1% sickle cell disease, 0.76% hemoglobin D Punjab (HbD Punjab), 0.32% hemoglobin C (HbC), and 0.22% hereditary persistence of fetal hemoglobin (HPFH).
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Paquistão
/
Fenótipo
/
Traço Falciforme
/
Humanos
/
Hemoglobina Fetal
/
Hemoglobinas Anormais
/
Programas de Rastreamento
/
Vigilância da População
/
Saúde da População Urbana
/
Prevalência
Tipo de estudo:
Estudo de prevalência
/
Estudo de rastreamento
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2002
Tipo de documento:
Artigo
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