Multifactorial pathogenic mechanisms of Burkholderia pseudomallei as suggested from comparison with Burkholderia cepacia.
Southeast Asian J Trop Med Public Health
;
1996 Mar; 27(1): 111-8
Artigo
em Inglês
| IMSEAR
| ID: sea-35769
ABSTRACT
With the purpose to elucidate the pathogenesis of disease due to Burkholderia pseudomallei some biological and biochemical properties of this species were studied in comparison with B. cepacia, since the difference in the level of virulence between the two species is remarkable despite of their toxonomic closeness. B. pseudomallei was distinct from B. cepacia in the capability to grow under anaerobic conditions, with positive nitrate respiration, excretion of high-molecular polysaccharides into liquid culture, and cytotoxicity against cultured tissue cells. From these observations together with our previous finding that B. pseudomallei can grow and survive in an acidic environment, we suggest multifactorial mechanisms for the pathogenesis of melioidosis due to B. pseudomallei.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Especificidade da Espécie
/
Virulência
/
Humanos
/
Microscopia Eletrônica
/
Técnicas Bacteriológicas
/
Burkholderia pseudomallei
/
Burkholderia cepacia
/
Sepse
/
Animais
/
Melioidose
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1996
Tipo de documento:
Artigo
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