Diversity of complement-mediated immune reaction to Trypanosoma gambiense.
Southeast Asian J Trop Med Public Health
;
1992 Mar; 23(1): 87-91
Artigo
em Inglês
| IMSEAR
| ID: sea-36188
ABSTRACT
Intact and papain-treated Trypanosoma gambiense clone populations, each expressing special antigens on their cell surfaces, were mixed with rabbit antiserum in the presence of complement. Two distinct types of immune reaction between trypanosomes and antisera were observed clumping followed by dissociation (CD) and inhibition of aggregation (IA). Special antigens on the cell surface of trypanosomes exposed after papain digestion are implicated in both types of immune reaction. IA was considered to be more effective as an immunological response which would allow the infected host to clear the pathogen without any obstruction of capillaries and impairment of blood flow caused by clumping masses of trypanosomes.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Coelhos
/
Ratos
/
Ratos Endogâmicos
/
Trypanosoma brucei gambiense
/
Tripanossomíase Africana
/
Masculino
/
Proteínas do Sistema Complemento
/
Sorotipagem
/
Estudos de Avaliação como Assunto
/
Animais
Tipo de estudo:
Estudo diagnóstico
/
Estudos de avaliação
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1992
Tipo de documento:
Artigo
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