Increased efficacy of liposomes-encapsulated praziquantel in treatment of opisthorchiasis in hamsters.
Southeast Asian J Trop Med Public Health
;
1983 Dec; 14(4): 501-4
Artigo
em Inglês
| IMSEAR
| ID: sea-36223
ABSTRACT
An increased efficacy of liposomes-encapsulated praziquantel was observed in the treatment of hamster opisthorchiasis. A single intracardial dose of 1.5 mg/kg of encapsulated praziquantel is as effective as an intracardial dose of 30 mg/kg or an oral dose of 100 mg/kg of free praziquantel. The suppressing activity of both free and liposomes-encapsulated praziquantel significantly decrease as the infection times increase from 1 to 5 weeks, suggesting that the young liver flukes are more susceptible to praziquantel than the adult flukes.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Opistorquíase
/
Praziquantel
/
Cricetinae
/
Mesocricetus
/
Isoquinolinas
/
Lipossomos
/
Animais
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1983
Tipo de documento:
Artigo
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