Therapy of chronic idiopathic thrombocytopenic purpura in adults: experiences from Thailand.
Southeast Asian J Trop Med Public Health
;
1993 ; 24 Suppl 1(): 71-5
Artigo
em Inglês
| IMSEAR
| ID: sea-36229
ABSTRACT
Results of different types of treatment in 416 adults with chronic idiopathic thrombocytopenic purpura (ITP) were analyzed. Of 368 patients treated with corticosteroids, 278 (77%) achieved complete response (CR ie, normalization of platelet count). However, only 18% of patients had continued complete response (CCR). Results of splenectomy was analyzed in 126 patients, 49% of them achieved CCR and 76% of them had beneficial effects from the operation. Emergency splenectomy was a life saving procedure in 8 of 11 patients with life-threatening hemorrhage. Vinca alkaloids gave a 50% transient CR. Immunosuppressive agents (cyclophosphamide, azathioprine) resulted in only 11% CCR.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Esplenectomia
/
Tailândia
/
Alcaloides de Vinca
/
Feminino
/
Humanos
/
Masculino
/
Prednisolona
/
Doença Crônica
/
Resultado do Tratamento
/
Púrpura Trombocitopênica Idiopática
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1993
Tipo de documento:
Artigo
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