Reticulocyte analysis in systemic lupus erythematosus and chronic renal failure using flow cytometry.
Asian Pac J Allergy Immunol
;
2000 Mar; 18(1): 23-7
Artigo
em Inglês
| IMSEAR
| ID: sea-36593
ABSTRACT
The number and maturation of circulating reticulocytes were measured in patients with systemic lupus erythematosus (SLE) and chronic renal failure (CRF) using an automated hematological analyzer (Technicon H*3 RTX) for their erythropoietic activities. Both SLE and CRF patients had increased reticulocyte numbers with a low degree of maturation. The SLE patients had no changes in mean reticulocyte corpuscular volume (MCVr) as compared to normal subjects (110.20 +/- 15.43 fl. in SLE and 110.39 +/- 5.09 fl. in normal), whereas CRF patients had significantly increased mean corpuscular reticulocyte volume (MCVr = 120.99 +/- 8.09 fl., p-value = 0.0019 as compared with normal). Three cases of SLE with nephrotic syndrome (NS) had high degree of MCVr (113.4, 125.0 and 133.1 fl., respectively). The renal involvement in SLE patients and CRF patients may associate with increased reticulocyte corpuscular volume.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Reticulócitos
/
Nefrite Lúpica
/
Humanos
/
Estudos de Casos e Controles
/
Contagem de Eritrócitos
/
Índices de Eritrócitos
/
Citometria de Fluxo
/
Anemia
/
Falência Renal Crônica
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Idioma:
Inglês
Revista:
Asian Pac J Allergy Immunol
Ano de publicação:
2000
Tipo de documento:
Artigo
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