Co-existence of HIV-1 subtypes B' and E infections among Thai injecting drug users.
Asian Pac J Allergy Immunol
;
2002 Mar; 20(1): 29-35
Artigo
em Inglês
| IMSEAR
| ID: sea-37111
ABSTRACT
Subtypes B' and E are the two major subtypes of HIV-1 among injecting drug users (IDU) in Thailand. However, there are not many reports on subtype distribution during the early epidemic. Random blood specimens collected during 1994-2000 from 3,286 IDU at the Thanyarak Hospital were tested for HIV antibody and subtyped by using peptide binding enzyme immunoassay. The prevalence rate of HIV infection was 36.8%. All HIV-seropositive IDU were ascertained for "year of first HIV seropositivity" from their medical records. Of 1,512 HIV-seropositive samples, 1,408 (93.1%) were typeable. During 1987-1988, the proportion of subtype B' was as high as 80% but decreased rapidly to 27.6% during 1999-2000. At the same time, the proportions of subtype E increased correspondingly (Chi-square test for the trend, p < 0.05). The relatively high proportion of subtype E among IDU since an early stage of the epidemic suggests early co-existence of both subtypes and needs further investigation.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ópio
/
Tailândia
/
Feminino
/
Humanos
/
Masculino
/
Infecções por HIV
/
Abuso de Substâncias por Via Intravenosa
/
Fatores Sexuais
/
Prevalência
/
Adolescente
Tipo de estudo:
Estudo de prevalência
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Asian Pac J Allergy Immunol
Ano de publicação:
2002
Tipo de documento:
Artigo
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