Pap smear, colposcopy and biopsy findings at follow-up of Pap smear positive women in North-east Thailand.
Artigo
em Inglês
| IMSEAR
| ID: sea-37541
ABSTRACT
As part of an ongoing project involving a large cohort in the Khon Kaen Province in the North-east of Thailand, a total of 236 women who had tested positive for a Pap smear at the initial recruitment and advised to seek medical attention were followed up after a mean period of 3.1 years. The 204 individuals who could be contacted were interviewed to determine treatments received and underwent a further Pap smear as well as colposcopy in 179 of the cases. On clinical advice, biopsies were also taken from 32 of these. Only 15% of the total of 204 had actually received therapy, the majority undergoing surgery (self-reported). Possible positive Pap smear results were obtained for 23.5%, with 6.4% having high grade squamous intraepithelial lesions (HGSILs) or squamous cell carcinoma (SCC) (one case). Comparison of the different testing modalities demonstrated 5.6% false negatives and 16.2 false positives for the Pap smear with colposcopy as the gold standard. Compared with biopsy findings, there were 21.8% and 40.6% false positives with Pap and colposcopy, respectively, but no false negatives. The present results point to good efficacy for the initial screening, since only 0.5% of the total population developed an SCC. However, judgement as to therapy should depend on a biopsy since there were considerable false positives with the other two modalities employed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Esfregaço Vaginal
/
Biópsia
/
Feminino
/
Humanos
/
Carcinoma de Células Escamosas
/
Displasia do Colo do Útero
/
Colo do Útero
/
Programas de Rastreamento
/
Seguimentos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Estudo de rastreamento
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2007
Tipo de documento:
Artigo
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