Geographical variation in the epidemiology of esophageal cancer in Pakistan.
Artigo
em Inglês
| IMSEAR
| ID: sea-37712
ABSTRACT
STUDY OBJECTIVES:
To evaluate whether factors such as the geographic area of residence, sex, and anatomic subsite of esophagus can prognosticate the histologic subtype of esophagus cancer.DESIGN:
To study the major histologic subtypes of esophagus cancer stratified by various factors through multivariate analyses using morphology as the dependent factor and gender, province, and subsite of esophagus as independent factors.SETTING:
A tertiary care cancer hospital situated in the city of Lahore in Pakistan. PATIENTS Three hundred and thirty five patients diagnosed either with esophageal squamous cell carcinoma or adenocarcinoma, from December 1994 to April 2004, were included. Subjects were residents of either Punjab or the Northwest Frontier Province in Pakistan. MAINRESULTS:
An excessive likelihood of development of squamous cell carcinoma versus adenocarcinoma was established for the Northwest Frontier Province as compared to Punjab (odds ratio 2.7, 95 percent confidence interval 1.2, 6.2, p = 0.02), and in the upper-third of the esophagus relative to the lower-third of the organ (odds ratio 8.8, 95 percent confidence interval 2.8, 28.3, p < 0.001).CONCLUSIONS:
This histologic variation may be explained by environmental and lifestyle factors peculiar to geographical regions.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Paquistão
/
Idoso de 80 Anos ou mais
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Neoplasias Esofágicas
/
Carcinoma de Células Escamosas
/
Adenocarcinoma
/
Modelos Logísticos
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Aged80
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2005
Tipo de documento:
Artigo
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