Granulomatous reaction in peripheral T-cell proliferative disease: a case report.
Artigo
em Inglês
| IMSEAR
| ID: sea-38460
ABSTRACT
A 52-year-old male presented with a prolonged fever, anemia, weight loss, hepatosplenomegaly, and elevated serum level of alkaline phosphatase. The patient developed septicemia, metabolic acidosis, and died 3 days after admission. Liver necropsy, tissue showed group C, peripheral T-cell proliferative disease. Epstein-Barr virus genomes were demonstrated in the nuclei of these abnormal T-cell lymphocytes. Granulomatous reaction was observed in the liver and bone marrow. Stains and cultures for mycobacteria and fungi gave negative results. Granulomatous reaction is believed to be induced by cytokines which were released from the T-cell lymphocytes that infiltrated in the liver and bone marrow.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Masculino
/
Linfoma de Células T Periférico
/
Hibridização In Situ
/
Evolução Fatal
/
Herpesvirus Humano 4
/
Granuloma
/
Fígado
/
Neoplasias Hepáticas
/
Pessoa de Meia-Idade
Idioma:
Inglês
Ano de publicação:
1997
Tipo de documento:
Artigo
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