Decreased suppressor T-lymphocytes in women who received progestogen injections.
Artigo
em Inglês
| IMSEAR
| ID: sea-38461
ABSTRACT
Decreased levels of suppressor T-cells (CD8+) were found in 17 normal women who received progestogen (Depoprovera) injection, 150 mg intramuscularly every three months for contraceptive purposes, for more than 30 months. The helper suppressor T-cells (CD4+ CD8+ ratio) was significantly elevated in this group compared to 30 normal female controls. No significant change of T-lymphocyte was found in 53 normal women who received the injection for less than 30 months or who received combined oral contraceptive pills. In conclusion, long term progestogen injection induced a lowering of suppressor T-cell levels, which is the same immunological change found in several autoimmune diseases.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Progesterona
/
Feminino
/
Humanos
/
Relação CD4-CD8
/
Linfócitos T Reguladores
/
Injeções Intramusculares
/
Contagem de Leucócitos
Idioma:
Inglês
Ano de publicação:
1992
Tipo de documento:
Artigo
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