Prevalence of thalassemia in pregnant women at Maharaj Nakorn Chiang Mai Hospital.
Artigo
em Inglês
| IMSEAR
| ID: sea-38528
ABSTRACT
OBJECTIVE:
To determine the prevalence of thalassemia including alpha-thalassemia-1 trait (SEA type), beta-thalassemia trait, hemoglobin E (HbE) trait, homozygous HbE, the combination of alpha-thalassemia-1 (SEA type) and beta-thalassemia trait, alpha-thalassemia-1 (SEA type) and hemoglobin E trait, and beta-thalassemia hemoglobin E disease in pregnant women.METHOD:
A cross-sectional descriptive study was conducted on pregnant women who attended the antenatal clinic at Maharaj Nakorn Chiang Mai Hospital, from 1 August to 31 October 2001. All subjects had blood taken for diagnosis of thalassemia trait or diseases, based on quantitative electrophoresis, and PCR (polymerase chain reaction) techniqueRESULTS:
516 pregnant women were recruited 81.0% resided in Chiang Mai province, and the remainder were in other northern provinces of Thailand. The mean (+/-SD) age was 27.7+/-6.3 years old. 5.6% of cases had anemia. Overall prevalence of thalassemia trait was 25.4% which were classified as follows alpha-thalassemia-1 (SEA type) trait 6.6%, beta-thalassemia trait 3.7%, hemoglobin E trait 11.6%, homozygous hemoglobin E 0.8%, the combination of alpha-thalassemia-1 (SEA type) and beta-thalassemia trait 1.2% and the combination of alpha-thalassemia-1 (SEA type) and hemoglobin E trait 1.5%. Additionally, the authors also found beta-thalassemia hemoglobin/E disease 0.2%.CONCLUSION:
The prevalence of thalassemia carriers among pregnant women at Maharaj Nakorn Chiang Mai hospital was high, indicating the necessity of a screening thalassemia program aimed at prevention and control of this disease.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Talassemia
/
Feminino
/
Humanos
/
Gravidez
/
Prevalência
/
Estudos Transversais
/
Adolescente
/
Pessoa de Meia-Idade
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2004
Tipo de documento:
Artigo
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