Low cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E.
Artigo
em Inglês
| IMSEAR
| ID: sea-40326
ABSTRACT
OBJECTIVE:
To evaluate hemoglobin E screening tests in a large scale of cases. MATERIAL ANDMETHOD:
A cross-sectional descriptive study was conducted Whole blood obtained from subjects was evaluated for CBC, OF, DCIP, and hemoglobin typing.RESULTS:
Five hundred twenty seven hemoglobin E and 280 reference subjects participated. DCIP's sensitivity, specificity, positive predictive value, and negative predictive value were 97.16%, 98.93%, 99.42%, and 95.19%, respectively. These values of OF were 69.12%, 80.00%, 86.67%, and 57.88%, respectively. In the combination of DCIP and OF gave rise to these values of 99.43%, 79.29%, 90.03%, and 96.67%, respectively. Finally the combination of DCIP and MCV < 80 fL resulted in these values to be 99.43%, 98.93%, 99.43%, and 98.93%, respectively. False positive and false negative rate were 1.07% and 0.57%, respectively.CONCLUSION:
Combination of DCIP and MCVwas better than that of DCIP and OF in hemoglobin E screening.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fragilidade Osmótica
/
Talassemia
/
Feminino
/
Humanos
/
Masculino
/
Hemoglobina E
/
Programas de Rastreamento
/
Estudos Transversais
/
Valor Preditivo dos Testes
/
Sensibilidade e Especificidade
Tipo de estudo:
Estudo diagnóstico
/
Avaliação Econômica em Saúde
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
/
Estudo de rastreamento
Idioma:
Inglês
Ano de publicação:
2008
Tipo de documento:
Artigo
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