Effect of oral estriol on urogenital symptoms, vaginal cytology, and plasma hormone level in postmenopausal women.
Artigo
em Inglês
| IMSEAR
| ID: sea-41214
ABSTRACT
OBJECTIVE:
To evaluate the effects of oral estriol on urogenital symptoms, vaginal cytology, and plasma follicle stimulating hormone (FSH) and estradiol level in postmenopausal women with urogenital symptoms.METHOD:
Twenty-eight postmenopausal women with urogenital symptoms who volunteered to participate in this study received 2 mg of oral estriol daily for 12 weeks. The urogenital symptoms, vaginal cytology, and plasma hormone level before and after treatment were analysed using paired t-test.RESULTS:
The genital and urological symptoms improved (P < 0.05) after treatment in all subjects. The vaginal cytology showed estrogenic effect on the karyopyknotic index and maturation value. There was a significantly (P < 0.05) higher level of plasma estradiol after 12 weeks of treatment. However, the difference of plasma FSH level before and after treatment was not statistically significant.CONCLUSION:
The daily oral estriol had a positive effect on the urogenital symptoms and vaginal cytology. The plasma estradiol increased after 12 weeks of treatment but the plasma FSH did not change.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sistema Urogenital
/
Vagina
/
Idoso
/
Feminino
/
Humanos
/
Administração Oral
/
Estudos Prospectivos
/
Resultado do Tratamento
/
Pós-Menopausa
/
Estradiol
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Ano de publicação:
2001
Tipo de documento:
Artigo
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