Treatment of adult acute myelogenous leukemia: a pilot study at Chulalongkorn Hospital.
Artigo
em Inglês
| IMSEAR
| ID: sea-41599
ABSTRACT
Twenty-seven patients with acute myelogenous leukemia (AML), aged 15 to 65 years, were treated with standard induction remission chemotherapy and two different strategies for postremission treatment. Seventeen patients (63%) achieved complete remission (CR). Nine patients (37%) died during marrow hypoplasia. The median survival of complete remitters allocated to the intensive postremission therapy is projected to be in excess of 24 months with 53 per cent probability of remaining in CR at two years. The median remission duration for patients who entered the nonintensive postremission therapy was 11 months. Age was the major factor significantly correlated with the outcome of treatment. It is concluded that intensive curative treatment should be indicated in AML patients who are less than 30 years.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Medula Óssea
/
Indução de Remissão
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Leucemia Mieloide Aguda
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Doxorrubicina
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1991
Tipo de documento:
Artigo
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