Intracranial metastasis of hepatic carcinomas: a study of 9 cases within 28 years.

ABSTRACT

A study was made on nine hepatic carcinomas with intracranial metastases. These cases brought a total number of reported intracranial metametastatic hepatic carcinomas to 32 instances. The secondary intracranial hepatic carcinomas formed a proportion of 1.3 to 2.9 per cent among intracranial metastatic tumors. Nine patients in this series were young with an average age of 37 years. There were five hepatocellular carcinomas and four cholangiocarcinomas. An intracranial secondary hepatocellular carcinoma in a 37-year-old man produced massive intracerebral hemorrhage. Only four cases including the current one have been described as massive intracerebral hemorrhage because of secondary hepatocellular carcinoma. Our case, moreover, had a high level of hematocrits representing a paraneoplastic syndrome.