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A cross-over trial comparing the effects of acebutolol and propranolol on the serum lipids and hypertension.
Indian Heart J ; 1989 Sep-Oct; 41(5): 292-5
Artigo em Inglês | IMSEAR | ID: sea-4274
ABSTRACT
A two-way cross-over trial comparing the effects of acebutolol and propranolol on the lipid profile was conducted. 50 patients were evaluated. The primary objective was to determine whether treatment by certain classes of beta-blockers induced deleterious effects on the serum lipids which could partially or wholly negate the beneficial effect of controlling hypertension. Each patient served as his/her own control, and received 6 weeks of therapy with acebutolol and 6 weeks of therapy with propranolol. The analysis of the results revealed that acebutolol did not have any adverse effect on the lipid profile in contrast to reports which implicate other beta-blockers in inducing pro-atherogenic changes in the serum lipid profile; but acebutolol and propranolol were equi-effective in controlling hypertension.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Propranolol / Feminino / Humanos / Masculino / Adulto / Hipertensão / Acebutolol / Lipídeos / Pessoa de Meia-Idade Idioma: Inglês Revista: Indian heart j Ano de publicação: 1989 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Propranolol / Feminino / Humanos / Masculino / Adulto / Hipertensão / Acebutolol / Lipídeos / Pessoa de Meia-Idade Idioma: Inglês Revista: Indian heart j Ano de publicação: 1989 Tipo de documento: Artigo