Use of Hachinski Ischemic Score in the memory clinic: Thai experience.
Artigo
em Inglês
| IMSEAR
| ID: sea-42756
ABSTRACT
BACKGROUND:
The validity ofHachinski Ischemic Score (HIS) in differentiating between Alzheimer's disease (AD) and Vascular dementia (VaD) has been questioned and compared with the gold standard autopsy.OBJECTIVE:
To confirm that the HIS can be used to differentiate related VaD from AD in a Thai population. MATERIAL ANDMETHOD:
A prospective study of 398 patients who were attending the Memory Clinic, at Siriraj Hospital between January 2001 and October 2003.RESULTS:
The 214 patients, with a mean age of 71.15 + 10.20 years, were classified as AD, VaD or mixed dementia (AD with cerebrovascular disease) in proportion of 60.2%, 30.4%, and 9.3% respectively. The authors propose HIS at 5 as a cut off point to differentiate patients with AD and those with VaD or AD with cerebrovascular disease with sensitivity of 85.3% and specificity of 72.9%.CONCLUSION:
The HIS can be applied to differentiate dementia related vascular etiology from AD in a Thai population.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Idoso de 80 Anos ou mais
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Demência Vascular
/
Estudos Prospectivos
/
Sensibilidade e Especificidade
/
Diagnóstico Diferencial
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Aged80
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2006
Tipo de documento:
Artigo
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