Reference value for urinary deoxypyridinoline as a specific marker for measuring bone resorption in Thais.
Artigo
em Inglês
| IMSEAR
| ID: sea-44401
ABSTRACT
In the next century, the increasing number of elderly and rising healthcare costs will bring with it metabolic bone problems, particularly osteoporosis. Deoxypyridinoline Dpd in urine is a sensitive and specific marker for screening and monitoring of bone resorption in a variety of diseases affecting bone turnover and in risk groups especially in the postmenopause. The reference value among aging (21-60 years) of a healthy well defined group was studied by collecting the urine between 700-1000 hours and using the ELISA technique to determine the level of Dpd. The reference value of Dpd in 113 males and 298 females 1.3-6.5 and 1.5-6.9 nm Dpd/nm Creatinine respectively. The level of Dpd in females was significantly higher than in males at p < 0.028. However, the average value of deoxypyridinoline in postmenopause was higher than premenopause but not different at p = 0.05. There are many factors which influence the results so the overall reference value is only a guideline for screening in bone resorption.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Valores de Referência
/
Tailândia
/
Reabsorção Óssea
/
Feminino
/
Humanos
/
Masculino
/
Biomarcadores
/
Adulto
/
Aminoácidos
/
Pessoa de Meia-Idade
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1999
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS