Cutaneous granuloma in systemic lymphoma: a case report in Thailand.

ABSTRACT

A 68-year-old woman presented with multiple erythematous infiltrative nodules and plaques on her face, trunk and extremities, 7 months after having complete remission from chemotherapy treatment of non-Hodgkin's lymphoma. Biopsy from the skin lesion showed tuberculoid granuloma without lymphoma. Special stains and culture were negative for micro-organism. Immunohistochemistry revealed polymorphic T and B cells infiltration without evidence of malignancy. The skin lesions subsided completely after corticosteroid treatment. Two months later, she developed brain involvement of lymphoma that responded well to radiation and chemotherapy.