Secondary hyperparathyroidism and calcium phosphate control in a hemodialysis population.
Acta Med Indones
;
2007 Apr-Jun; 39(2): 71-4
Artigo
em Inglês
| IMSEAR
| ID: sea-47107
ABSTRACT
AIM:
To evaluate the prevalence of secondary hyperparathyroidism and calcium phosphate control in the hemodialysis Asian population.METHODS:
We evaluated 36 patients at Tan Tock Seng Hospital in Singapore, who were receiving thrice weekly maintenance hemodialysis for at least 6 months. Patients with history of previous parathyroidectomy were excluded from the study. Patient's weight, length of dialysis per week, duration of dialysis, serum calcium, phosphate, albumin, bicarbonate, intact parathyroid hormone (iPTH), and single pool Kt/V were retrieved from patient's medical records.RESULTS:
The mean length of weekly dialysis session and single pool Kt/V was 13.5 hours and 1.73 respectively. The majority of patients achieved the target range of serum phosphorus (67%), corrected calcium (58%) and calcium times phosphate (Ca ' P) product (81%). Only 25% of patients had levels of iPTH within the target range (150-300 pg/mL). Ninety four percent of the patients were on calcium-based phosphate binder and 42% on vitamin D therapy. A significant number of patients still fell out of the recommended guideline range for serum concentrations of phosphorus (11% of patients below lower target range, 22% of patients above upper target range), corrected calcium (3% below, 39% above), calcium-phosphorus product (19% above), and iPTH (58% below, 17% above). Thirty percent of the patients had levels of iPTH < 100 pg/mL.CONCLUSION:
Compared to data reported from the USA, Europe and Japan, mean levels of phosphate, corrected calcium and Ca ' P product seem better controlled in this hemodialysis Asian population. However, more than half of the patients may have oversuppression of iPTH levels and a third of patients are at increased risk of developing a dynamic bone disease.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fosfatos
/
Singapura
/
Doenças Ósseas
/
Feminino
/
Humanos
/
Masculino
/
Fosfatos de Cálcio
/
Cálcio
/
Prevalência
/
Estudos Prospectivos
Tipo de estudo:
Estudo de etiologia
/
Guia de Prática Clínica
/
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Acta Med Indones
Ano de publicação:
2007
Tipo de documento:
Artigo
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