Exfoliative cytology in screening for malignant and premalignant lesions in the buccal mucosa.
Ceylon Med J
;
1998 Dec; 43(4): 206-9
Artigo
em Inglês
| IMSEAR
| ID: sea-47423
ABSTRACT
OBJECTIVE:
To test the efficacy of exfoliative cytology in the detection of oral premalignant and malignant lesions.DESIGN:
Cytological diagnosis of lesions of the buccal mucosa assessed using histopathological diagnosis of the same lesions as the gold standard.SUBJECTS:
Patients with buccal lesions clinically diagnosed as leukoplakia (n = 91) and squamous cell carcinoma (SCC, n = 59), and healthy subjects (n = 40) in whom buccal mucosa appeared clinically normal.SETTING:
Oral and Maxillo-facial Unit, General Hospital, Kandy and Department of Pathology, Faculty of Medicine, University of Peradeniya.RESULTS:
A sensitivity of 77%, specificity of 100% and accuracy of 92% were obtained for leukoplakia. SCC gave a sensitivity of 94%, specificity of 100% and an accuracy of 95%.CONCLUSIONS:
Oral exfoliative cytology is a useful method for detecting oral premalignant and malignant lesions. Anucleated squames in a smear is non-diagnostic.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Lesões Pré-Cancerosas
/
Humanos
/
Leucoplasia Oral
/
Neoplasias Bucais
/
Carcinoma de Células Escamosas
/
Bochecha
/
Sensibilidade e Especificidade
/
Citodiagnóstico
/
Mucosa Bucal
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Idioma:
Inglês
Revista:
Ceylon Med J
Ano de publicação:
1998
Tipo de documento:
Artigo
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