Protective effective of vitamin E in kidney storage solution on renal tissue metabolism in rats.
Ceylon Med J
;
1995 Sep; 40(3): 97-100
Artigo
em Inglês
| IMSEAR
| ID: sea-48122
ABSTRACT
OBJECTIVE:
To determine whether inclusion of vitamin E into kidney storage solutions protects metabolism and tubular ultrastructure of stored rat kidney.METHODS:
Rat kidneys were flush stored in Marshall's Citrate (MC) and MC + vitamin E (25% of LD 50 and 50% of LD 50) for 24 hours at 0 degrees C. After storage kidney slices were tested for gluconeogenesis and lactate dehydrogenase (LDH) activity, and examined for cellular ultrastructure.RESULTS:
Kidneys stored in MC + vitamin E gave higher gluconeogenesis than those stored in MC alone (p < 0.001). Tubular ultrastructure was better preserved in the presence of Vitamin E.CONCLUSIONS:
Vitamin E appears to protect the metabolism and ultrastructure of stored rat kidneys.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Preservação de Órgãos
/
Ratos
/
Vitamina E
/
Ratos Sprague-Dawley
/
Gluconeogênese
/
Rim
/
Animais
Idioma:
Inglês
Revista:
Ceylon Med J
Ano de publicação:
1995
Tipo de documento:
Artigo
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