Changing patterns of thyroid cancer in Sri Lanka. Has the iodination programme helped?
Artigo
em Inglês
| IMSEAR
| ID: sea-48669
ABSTRACT
OBJECTIVES:
To ascertain if there has been a change in the pattern of thyroid cancer in Sri Lanka. If so, whether there is a correlation to the implementation of the programme of iodination.DESIGN:
Retrospective (1974-1986) and prospective (1987-2001).SETTING:
Kandy Hospital (1974-1982), Peradeniya Hospital (1982-2001) and private hospitals in Kandy (1979-2001).METHOD:
Three hundred consecutive patients with cancer of the thyroid seen over 28 years (1974-2001) period were reviewed for demography, histopathology and extent of spread at presentation. Seventy one patients of this group had a pre-existing goitre of greater than 10 years' duration and were similarly reviewed.RESULTS:
A highly significant reduction of anaplastic thyroid cancer and a highly significant reduction in the extent of extra-thyroidal spread at presentation of differentiated thyroid cancer were observed after 1995. In malignancy supervening on pre-existing goitre, a significant reduction in anaplastic carcinoma and a highly significant increase in papillary carcinoma were noted in the post-1996 period. A significant reduction of extra-thyroidal spread was also observed.CONCLUSION:
A trend towards more differentiated thyroid cancer with lesser degree of spread was observed in recent years. The iodination programme implemented in 1995 is likely to be responsible for this change.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sri Lanka
/
Humanos
/
Neoplasias da Glândula Tireoide
/
Carcinoma Papilar
/
Estudos Prospectivos
/
Estudos Retrospectivos
/
Carcinoma Papilar, Variante Folicular
/
Adulto
/
Iodo
Tipo de estudo:
Estudo observacional
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2003
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS