Biological behaviour of moderate dysplasia--a prospective study.
Indian J Cancer
;
1996 Mar; 33(1): 24-30
Artigo
em Inglês
| IMSEAR
| ID: sea-49431
ABSTRACT
The present communication reports the biological behaviour of women with moderate dysplastic lesions of uterine cervix based on a long term prospective study. Two hundred and thirty nine women with moderate dysplasia by cervical cytology who satisfied the criteria for registration were longitudinally followed up at 3 +/- 1 monthly intervals along with age and parity matched controls for a period ranging from 4 to 132 months. The cumulative rate of progression from moderate dysplasia to malignancy (CIS) was observed to be 23.0% at the end of 72 months of follow up with mean transition interval of 24.2 months. Out of 239 cases, 142 women who had more than 24 months of follow up were considered for studying the biological behaviour of the lesion. It was observed that during a follow up of 132 months, 14(9.9%) and 15(10.6%) women progressed to carcinoma in-situ and severe dysplasia respectively. The persistence of lesion was observed in 21(14.8%) women while 11(7.3%) and 81(57.0%) regressed to mild dysplasia and normalcy respectively.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Carcinoma in Situ
/
Displasia do Colo do Útero
/
Neoplasias do Colo do Útero
/
Estudos Prospectivos
/
Seguimentos
/
Estudos Longitudinais
/
Progressão da Doença
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian J Cancer
Ano de publicação:
1996
Tipo de documento:
Artigo
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