Adjuvant therapy in invasive thymoma: an audit of cases treated over an 8 year period.
Indian J Cancer
;
1999 Mar; 36(1): 46-56
Artigo
em Inglês
| IMSEAR
| ID: sea-49925
ABSTRACT
Invasive thymomas comprise 0.1%-0.2% of all malignancies in India. This report is an audit of 11 cases (10 males and 1 female) at a mean age of 36.6 years (range 25-52 years) of invasive thymoma accrued over an eight year period treated by combined modality treatment. Nine of these presented with myaesthenia gravis. All patients underwent initial surgery (3 partial and 8 total resections) and postoperative radiotherapy. Two of the three partially resected patients received one course of chemotherapy prior to radiotherapy consisting of cyclophosphamide, vincristine, procarbazine and prednisolone. At a median follow up of 28 months (range 2-87) there have been no local relapses, one distant metastasis and one death due to uncontrolled myaesthenia. The treatment strategies with invasive thymomas would depend upon the extent of resection. Postoperative radiotherapy appears to be indicated in all cases, however the role of chemotherapy may be limited to those with partial resection.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Procarbazina
/
Timectomia
/
Timoma
/
Neoplasias do Timo
/
Vincristina
/
Feminino
/
Humanos
/
Masculino
/
Prednisolona
/
Protocolos de Quimioterapia Combinada Antineoplásica
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian J Cancer
Ano de publicação:
1999
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS