Primary hyperparathyroidism--an Indian study.
Indian J Cancer
;
1994 Jun; 31(2): 72-7
Artigo
em Inglês
| IMSEAR
| ID: sea-50252
ABSTRACT
Twenty eight patients of sporadic primary hyperparathyroidism seen over a period of 10 years were studied. There were 18 females and 10 males with a mean age of 35.9 years. Bone involvement was the commonest clinical presentation (90%) followed by renal involvement (65%) and more than half the patients (54%) had involvement of both the skeletal and renal systems. The tumor was clinically palapable in six patients. Thalliumtechnetium subtraction scan had a sensitivity of 87% followed by computerised tomography (70%), and ultrasound (65%) in diagnosing parathyroid pathology. All the patients underwent surgical excision of the abnormal gland (S). Adenomas constituted the single largest group (90%). Histologically, only 32% of the patients had chief cell morphology. Clear cell (32%) mixed cell, and oxyphil cell (7.2%) types accounted for the remaining adenomas. Majority of the patients (82%) had symptomatic postoperative hypocalcemia requiring intravenous calcium with or without vitamin D supplementation. In contrast to western reports most of our patients were young, presented late with florid bone and renal disease and had large palpable tumors.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias das Paratireoides
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Adenoma
/
Criança
/
Cálcio
/
Estudos Retrospectivos
/
Adolescente
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
Indian J Cancer
Ano de publicação:
1994
Tipo de documento:
Artigo
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