The role of Wobe-Mugos in reducing acute sequele of radiation in head and neck cancers--a clinical phase-III randomized trial.
Indian J Cancer
;
1999 Jun-Dec; 36(2-4): 141-8
Artigo
em Inglês
| IMSEAR
| ID: sea-51206
ABSTRACT
Oral enzymes act as a potent antiinflammatory, antiedematous agents thereby decreasing acute toxigenic effect of radiation and increasing compliance, quality of life of our patients. Fifty patients were randomized 25 allocated in enzyme and radiotherapy arm, 25 in radiotherapy alone. Pre RT and post RT biopsies were taken from both arms. In our study it was found that there was clinical, histopathological as well as statistical significant difference in both arms. The enzyme arm patients had mucostis of grade I in 76%, grade II in 12%, grade III in 8% while as 8% had grade I, 68% grade II, 24% had grade III in RT arm alone. In enzyme patients skin reactions of grade I in 72%, 20% had grade II, 8% had grade III. In control arm 12% had grade I, 76% had grade II, 8% had grade III skin reaction.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Extratos Pancreáticos
/
Radiodermite
/
Extratos do Timo
/
Humanos
/
Quimotripsina
/
Carcinoma de Células Escamosas
/
Papaína
/
Tripsina
/
Adjuvantes Imunológicos
/
Doença Aguda
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
Idioma:
Inglês
Revista:
Indian J Cancer
Ano de publicação:
1999
Tipo de documento:
Artigo
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