Cytological study of copper in oral submucous fibrosis.
Article
em En
| IMSEAR
| ID: sea-51870
BACKGROUND: Habitual arecanut chewing is associated with Oral Submucous Fibrosis (OSF). High copper content in arecanut plays a vital role in pathogenesis of OSF. This study evaluates the copper-staining pattern of buccal epithelial cells in oral cytological smears of non-chewers, chewers, and OSF. MATERIALS & METHODS: Alcohol fixed buccal epithelial smears of 10 histopathologically confirmed cases of OSF, 10 chewers without lesion, and 5 nonchewers were stained with modified Rhodamine technique and studied under the light microscope. Buccal epithelial smears of non-chewers dipped in copper sulphate solution were used as known positive for copper. RESULT: Copper appeared as shades of palered within the cytoplasm of chewers and did not show any stain in non-chewers. Intense red stain was seen in OSF smears as dark granules within the cytoplasm. CONCLUSION: Intense staining of copper in OSF buccal smears, than in the chewers supports the role of copper in the pathogenesis of OSF.
Texto completo:
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Índice:
IMSEAR
Assunto principal:
Fibrose Oral Submucosa
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Areca
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Rodaminas
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Humanos
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Cobre
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Citoplasma
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Células Epiteliais
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Corantes Fluorescentes
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Mucosa Bucal
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article