CD-3 positive extranodal T-cell lymphoma of nasal type with skin involvement.
Indian J Dermatol Venereol Leprol
;
2006 May-Jun; 72(3): 215-7
Artigo
em Inglês
| IMSEAR
| ID: sea-52747
ABSTRACT
A 40-year-old previously healthy lady presented with nasal obstruction and localized plaques over the right arm. She developed complete nasal obstruction due to a mass in the right nasal cavity and skin lesions that ulcerated to present as ecthyma gangrenosum like lesions. Patient's condition deteriorated fast and she developed icterus with fatal outcome within 4 weeks of developing skin lesions. Nasal and skin biopsy revealed angiocentric T-cell lymphoma, which on immuno-phenotyping revealed CD-3 positive; and CD-20, CD-30, ALK and EMA negativity. She was seronegative for HIV. Final diagnosis of CD-3 positive extranodal T-cell lymphoma of nasal type was made. Extranodal T-cell lymphomas are very aggressive NHLs with poor prognosis. Prognosis depends on histology, stage of the disease and sites of involvement. NK/T cell lymphoma of nasal type is common with EBV association. Skin involvement is rare and is also an indicator of poor prognosis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Cutâneas
/
Feminino
/
Humanos
/
Neoplasias Nasais
/
Linfoma de Células T
/
Complexo CD3
/
Evolução Fatal
/
Adulto
/
Ectima
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Indian J Dermatol Venereol Leprol
Ano de publicação:
2006
Tipo de documento:
Artigo
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