An unusual seroconversion profile in a pregnant woman infected with the human immunodeficiency virus-1: need for using later generations HIV screening assays.
Indian J Med Microbiol
;
2008 Oct-Dec; 26(4): 390-2
Artigo
em Inglês
| IMSEAR
| ID: sea-53881
ABSTRACT
The first HIV-1 marker that appears in blood following infection is HIV-1 RNA and usually the load is in millions of copies/ ml preceding seroconversion. A 24-year-old pregnant woman, gravida 2, parity 1 was tested for HIV as part of antenatal screening. Three samples were collected and tested from this individual over a period 70 days. The HIV-1 RNA level during seroconversion phase was very low, contrary to the well understood natural history of HIV infection. The reactivity rate in the ELISA and the Western Blot profile showed a gradual increase over the 70 days with a weak reactivity in a second generation assay (detects IgG only) for the third sample. This case illustrates the uncertainties regarding the serological window period in HIV infection and the need to use at least a third generation assay in testing centres for early detection of HIV infection.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Complicações Infecciosas na Gravidez
/
Fatores de Tempo
/
Feminino
/
Humanos
/
Gravidez
/
RNA Viral
/
Ensaio de Imunoadsorção Enzimática
/
Sorodiagnóstico da AIDS
/
Anticorpos Anti-HIV
/
Infecções por HIV
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Estudo de rastreamento
Idioma:
Inglês
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2008
Tipo de documento:
Artigo
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