Investigation of T cell receptors in the peripheral blood of patients with active pulmonary tuberculosis.
Indian J Med Microbiol
;
2009 Jan-Mar; 27(1): 40-3
Artigo
em Inglês
| IMSEAR
| ID: sea-53930
ABSTRACT
T cells have the capability of recognizing target cells through their T cell receptors (TCRs). Thus, the percentages of CD3+/gamma-delta (gammadelta) TCR+ and CD3+/alpha-beta (alphabeta) TCR+ T lymphocytes were investigated in active and inactive pulmonary tuberculosis (PT) patients and in healthy individuals. CD3+ and CD3+/alphabeta TCR+ cell percentages were significantly lower in all PT patients than in healthy subjects. Percentages of CD3+/gammadelta and CD3+/alphabeta TCR+ were not statistically different between active and inactive PT patients. It was concluded that alphabeta TCR+ T cells might have a protective role in tuberculosis infection.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tuberculose Pulmonar
/
Sangue
/
Feminino
/
Humanos
/
Masculino
/
Receptores de Antígenos de Linfócitos T
/
Linfócitos T
/
Subpopulações de Linfócitos T
/
Complexo CD3
/
Adulto
Idioma:
Inglês
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2009
Tipo de documento:
Artigo
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