Prevalence of HCV infection in patients on haemodialysis: survey by antibody and core antigen detection.
Indian J Med Microbiol
;
2005 Apr; 23(2): 106-10
Artigo
em Inglês
| IMSEAR
| ID: sea-54205
ABSTRACT
PURPOSE:
The present study was undertaken to determine the prevalence of HCV infection by antibody testing and HCV core antigen (HCVcAg) determination by ELISA in haemodialysis patients and to evaluate the HCV c Ag assay in the detection of HCV infected patients on haemodialysis. MATERIALS ANDMETHODS:
A total of 151 chronic renal failure patients on haemodialysis from May 2003 to October 2004 were studied. One hundred patients out of 151 were followed for 2-5 months. All the patients were tested for anti HCV and HCV core antigen once a month. Anti HCV ELISA positive specimens were confirmed by RIBA.RESULTS:
The overall prevalence of HCV infection was 13.23%. Antibody positivity was observed in 9.93% and HCVcAg alone was detected in 2.64%. One patient (0.66%) was initially positive for core antigen and later seroconverted.CONCLUSIONS:
Screening for HCV antibodies alone does not exclude infection with HCV in patients on haemodialysis and HCVcAg may be a useful test for identifying HCV infected patients on haemodialysis in the early phase of infection before seroconversion.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Anticorpos Anti-Hepatite
/
Estudos Soroepidemiológicos
/
Proteínas do Core Viral
/
Prevalência
/
Diálise Renal
/
Hepatite C
/
Hepacivirus
/
Antígenos da Hepatite C
/
Índia
Tipo de estudo:
Estudo diagnóstico
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2005
Tipo de documento:
Artigo
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